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Premarin should have never been prescribed without further testing because of a huge cancer risk when taking the hormone replacemen.

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Estrogen should not be used to prevent heart diseasestrokeor dementiaThis medicine may actually increase your risk of developing these conditions.

This medication passes into breast milkIt may reduce the quality and amount of breast milk producedConsult your doctor before breast-feeding.

For initiation and continuation of treatment of postmenopausal symptomsthe lowest effective dose for the shortest durationsee section 4.4should be usedTreatment to control menopausal symptoms should be initiated with Premarin 0.3mgIf symptoms are not adequately controlledhigher doses of Premarin may be prescribedOnce treatment is established the lowest effective dose necessary for the relief of symptoms should be usedPatients should be re-evaluated periodically to determine if treatment for symptoms is still necessary.

Tell your doctor if you just had or will be having surgeryor if you will be confined to a chair or bed for a long timesuch as a long plane flightThese conditions increase your risk of getting blood clotsespecially if you are taking an estrogen productYou may need to stop this medication for a time or take special precautions.

If you are taking the extended-release tabletsdo not crushchewor dissolve themDoing so can release all of the drug at onceincreasing the risk of side effectsAlsodo not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do soSwallow the whole or split tablet without crushing or chewing.

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premarin vaginal cream may also affect how your other medicines work.