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Rarely, high doses of cyclically pulsed intravenous methylprednisolone usually for the treatment of exacerbations of multiple sclerosis at doses of 1 g day can induce a toxic form of acute hepatitis, discontinue therapy if it occurs, since recurrence has occurred after re-challenge, avoid use in patients with a history of toxic hepatitis caused by methylprednisolone.

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This medication may mask signs of infectionIt can make you more likely to get infections or may worsen any current infectionsThereforewash your hands well to prevent the spread of infectionAvoid contact with people who have infections that may spread to otherssuch as chickenpoxmeaslesfluConsult your doctor if you have been exposed to an infection or for more details.

You should not stop using prednisolone suddenlyFollow your doctor’s instructions about tapering your dose.

In childrenthe dose may be lower than for an adult with the same illness because it is calculated according to their height and weight.

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