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Nerve problemsconfusionweaknessdrowsinesscoordination problemsfeeling irritableheadacheneck stiffnessvision problemsloss of movement in any part of your bodyor.

Temporary hair loss may occurNormal hair growth should return after treatment has ended.

Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatmentsIt may also be used tocontrol juvenile rheumatoid arthritisMethotrexate belongs to a class of drugs known as antimetabolitesIt works by slowing or stopping the growth of cancer cells and suppressing the immune system.

Methotrexate use has rarely caused serioussometimes fatalside effectssuch as lung problemslung infectionsPneumocystis jiroveci pneumoniaskin reactionsdiarrheaand mouth soresulcerative stomatitisSee also Side Effects section

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for many years men were advised not to father children while they were on methotrexate and for at least 3 months afterwards, because methotrexate had been reported to cause a reduction in sperm count.