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Taking zyban late at night can make it harder to sleep.

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Taking MAO inhibitors with this medication may cause a seriouspossibly fataldrug interactionAvoid taking MAO inhibitorsisocarboxazidlinezolidmethylene bluemoclobemidephenelzineprocarbazinerasagilinesafinamideselegilinetranylcypromineduring treatment with this medicationMost MAO inhibitors should also not be taken for two weeks before and after treatment with this medicationAsk your doctor when to start or stop taking this medication.

The recommended dose of Zyban must not be exceededsince bupropion is associated with a dose-related risk of seizureAt doses up to the maximum recommended daily dose300mg of Zyban dailythe incidence of seizures is approximately 0.11/1,000

For the first three daysusers will take one 0.5mg pill per dayOn day fourthis may be upped to one 0.5mg pill taken twice per dayFrom day eightusers may be advised to move on to the 1mg tabletstaking one twice a day.

Bupropion chloride was originally prescribed as an antidepressantIn 1997the FDA approved it as the first medication to help people stop smokingsold under the name Zyban.

Zyban tablets should be swallowed wholeThe tablets should not be cutcrushed or chewed as this may lead to an increased risk of adverse effects including seizures.

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