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Symptomatic individuals seek treatment t s ; p and are prescribed either cefixime p cef or another antibiotic p oth .
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cefixime is generally effective in the eradication of s pyogenes from the nasopharynx; however, its efficacy in the . subsequent prevention of rheumatic fever has not been established.
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as a result of the studies, it has been observed that the formulations, in which effervescent couple cefixime ratio is in the range of 15 1 to 3 1, preferably 12 1 to 3 1, more preferably 8 1 to 4 1 , disintegrate rapidly in water and cefixime active agent which has low water solubility dissolves easily in water.
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