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Skipping doses or not completing the full course of therapy may 1 decrease the effectiveness of the immediate treatment and 2 increase the likelihood that bacteria will develop resistance and will not be treatable by cefixime trihydrate for oral suspension or cefixime trihydrate chewable tablets or other antibacterial drugs in the future.
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in one study in a limited number of adults undergoing hemodialysis and receiving 400-mg oral doses of cefixime, pharmacokinetics of the drug were similar to those reported for patients with creatinine clearances of 21-60 ml minute.
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the recommended treatment for gonorrhea is ceftriaxone 125 mg intramuscularly or cefixime 400 mg orally.
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in this aspect, the present invention is related to the effervescent formulation, in which effervescent couple cefixime ratio is in the range of 15 1 to 3 1, preferably 12 1 to 3 1, more preferably 8 1 to 4 1.
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cefixime is generally effective in the eradication of s pyogenes from the nasopharynx; however, its efficacy in the subsequent prevention of rheumatic fever has not been established.
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